You can have your details entered into 1 of the 2 registries that are part of the EUROPAC study

• The 1st registry is for people who have pancreatic cancer in their family
• The 2nd registry is for people who have a family history of inflammation of the pancreas (pancreatitis)

The following bullet points list the entry conditions for this study. Talk to the study team if you are unsure about any of these. They will be able to advise you

Who can take part

1. Registry:

You may be able to join the registry if at least one of the following apply:

• That in your family there are 2 first degree relatives who have or had adenocarcinoma pancreatic cancer, that is parent and child, brothers or sisters
• You have 3 or more relatives with adenocarcinoma pancreatic cancer
• You have a medical condition that increases your risk of pancreatic cancer for example hereditary non polyposis colorectal cancer (HNPCC), familial atypical multiple mole melanoma (FAMMM) and Lynch syndrome. And 1 family member who has pancreatic cancer
• Your family has a gene known to cause pancreatic cancer for example BRCA2 and at least 1 member has pancreatic cancer
• You have 2 or more relatives that have inflammation of the pancreas (pancreatitis) where the cause is unknown (idiopathic)
• There is at least 1 person in your family that has inflammation of the pancreas caused by a known change (mutation) in the PRSS1 gene

2. Screening:

Inclusion criteria

When you are registered the study team will assess your lifetime risk of getting pancreatic cancer

Depending on this outcome they will offer you the choice to join the secondary screening programme

Exclusion criteria

For the screening study the researchers carry out an assessment of your cancer risk

They use this and their knowledge of your family to determine if you can take part

You won’t be able to take part if the chance of you developing pancreatic cancer in the next 3 years is less than 2 out of every 100 (less than 2%)

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