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Pernicious Anaemia

  

Pernicious anaemia is associated with autoimmune atrophic gastritis which has an increased risk of gastric cancer.


Pernicious anaemia is associated with autoimmune atrophic gastritis which has an increased risk of gastric cancer.

The recommendations are –

  • A single endoscopy should be performed to identify prevalent lesions (carcinoid tumours and gastric cancer) in pernicious anaemia.
  • Consider 3 yearly endoscopy surveillance in patients with EXTENSIVE gastric atrophy, but not in mild-moderate cases (poor evidence, based on consensus)

In summary, a single endoscopy is reasonable in confirmed Pernicious anaemia and if there are any abnormalities, then further surveillance to be considered on individual case basis.

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